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Images of Memorable Cases: Case 1

Module by: Herbert L. Fred, MD, Hendrik A. van Dijk. E-mail the authorsEdited By: Frederick Moody

http://rup.rice.edu/memcases-button.jpg

Case_1-pres1-1.jpg

Case_1-pres1-2.jpg

Case_1-pres1-3.jpg

This man could not walk or open his hands because of the pain induced by the lesions on his soles and palms. He had no oral complaints.

A heredofamilial ectodermal defect transmitted as a mendelian dominant, affecting all races, and appearing in both sexes with about equal frequency. Hyperkeratosis of the palms and soles characterize this disorder, but involvement of the gums and tongue—especially to the extent exhibited by this patient—has not been described heretofore. Moreover, the degree of keratosis of his feet (image below) is remarkable, perhaps unique.

Case_1-diag1-1.jpg

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