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Images of Memorable Cases: Case 117 & 118

Module by: Herbert L. Fred, MD, Hendrik A. van Dijk

http://rup.rice.edu/memcases-button.jpg

Case_117_118-pres1-1.jpg Case_117_118-pres1-2.jpg

These two unrelated patients—a 14-year-old boy (left) and a 23-year-old woman (right)—have the same disease.

117 & 118. Multiple endocrine neoplasia, Type IIB (MEN- IIB)

An inherited, autosomal dominant disease characterized by medullary thyroid carcinoma, pheochromocytoma, and mucosal neuromas, associated at times with prognathism, puffy lips, and bony abnormalities. Both of these patients had surgically treated medullary thyroid carcinoma, neuromas of the tongue and lips, and prognathism. Neither, however, had any evidence, as yet, of adrenal disease.

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