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Images of Memorable Cases: Case 143

Module by: Herbert L. Fred, MD, Hendrik A. van Dijk

http://rup.rice.edu/memcases-button.jpg

Case_143-pres1-1.jpg

This 17-year-old mentally retarded girl had tonic- clonic seizures since childhood.

143. Tuberous sclerosis

A hereditary condition transmitted in an autosomal dominant fashion with variable expressivity. Shown in the image are the pathognomonic facial angiofibromas (adenoma sebaceum) that occur in about 50% of these patients.

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