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Images of Memorable Cases: Case 148

Module by: Herbert L. Fred, MD, Hendrik A. van Dijk. E-mail the authorsEdited By: Frederick Moody

http://rup.rice.edu/memcases-button.jpg

Case_148-pres1-1.jpg

This 62-year-old Caucasian diabetic said that his skin was slowly getting darker. On examination, he had an enlarged, firm liver and diffusely hyperpigmented skin with a deep bronze tint, especially prominent over the legs. (The intern’s leg serves as control.)

This case is a classic example of “bronzed diabetes.” The patient had elevated serum levels of iron and ferritin, along with increased transferrin saturation. His liver biopsy showed cirrhosis with excessive iron.

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