Skip to content Skip to navigation

Connexions

You are here: Home » Content » Images of Memorable Cases: Case 26

Navigation

Content Actions
  • Download module PDF
  • Add to ...
    Add the module to:
    • My Favorites
    • A lens
    • An external social bookmarking service
    • My Favorites (What is 'My Favorites'?)
      'My Favorites' is a special kind of lens which you can use to bookmark modules and collections directly in Connexions. 'My Favorites' can only be seen by you, and collections saved in 'My Favorites' can remember the last module you were on. You need a Connexions account to use 'My Favorites'.
    • A lens (What is a lens?)

      Definition of a lens

      Lenses

      A lens is a custom view of Connexions content. You can think of it as a fancy kind of list that will let you see Connexions through the eyes of organizations and people you trust.

      What is in a lens?

      Lens makers point to Connexions materials (modules and collections), creating a guide that includes their own comments and descriptive tags about the content.

      Who can create a lens?

      Any individual Connexions member, a community, or a respected organization.

    • External bookmarks
  • E-mail the authors

Lenses

What is a lens?

Definition of a lens

Lenses

A lens is a custom view of Connexions content. You can think of it as a fancy kind of list that will let you see Connexions through the eyes of organizations and people you trust.

What is in a lens?

Lens makers point to Connexions materials (modules and collections), creating a guide that includes their own comments and descriptive tags about the content.

Who can create a lens?

Any individual Connexions member, a community, or a respected organization.

This content is ...

Affiliated with (What does "Affiliated with" mean?)

This content is either by members of the organizations listed or about topics related to the organizations listed. Click each link to see a list of all content affiliated with the organization.
  • Ricepress

    This module is included inLens: Rice University Press Titles
    By: Rice University PressAs a part of collection:"Images of Memorable Cases: 50 Years at the Bedside"

    Click the "Ricepress" link to see all content affiliated with them.

Also in these lenses

  • Printable Books

    This module is included inLens: Connexions Books Available for Print on Demand
    By: ConnexionsAs a part of collection:"Images of Memorable Cases: 50 Years at the Bedside"

    Comments:

    "This book is available in full color in three different formats, published by Rice University Press. It presents a series of interesting medical cases and the eventual diagnosis of each one. "

    Click the "Printable Books" link to see all content selected in this lens.

  • Rice University Press

    This module is included inLens: Rice University Press
    By: Frederick MoodyAs a part of collection:"Images of Memorable Cases: 50 Years at the Bedside"

    Click the "Rice University Press" link to see all content selected in this lens.

Recently Viewed

Tags

(What is a tag?)

These tags come from the endorsement, affiliation, and other lenses that include this content.

Images of Memorable Cases: Case 26

Module by: Herbert L. Fred, MD, Hendrik A. van Dijk

Case_26-pres1-1.jpg

Normal conjunctival circulation (approximately x35).

Case_26-pres1-2.jpg

Conjunctiva of a profoundly anemic teenager (approximately x30).

26. Sickle cell disease

Inspection of the conjunctiva with the +40 lens of the ordinary ophthalmoscope can be a useful adjunct to the diagnosis of certain types of sickle cell disease, particularly the homozygous form. The characteristic sign consists of sharply defined, dark-red, comma-shaped or corkscrew-shaped vessel fragments that appear isolated from the rest of the conjunctival circulation. These anomalous segments are visible primarily in that part of the lower bulbar conjunctiva covered by the lid.

The pathogenesis of this conjunctival sign remains speculative. There is evidence, however, that endothelial proliferation with trapping of erythrocytes occurs in the distal portion of some capillaries; immediately proximal to such involvement, the vessels are dilated and thin-walled. Infusion of blood or inhalation of oxygen can modify, if not temporarily eliminate, the sign. Conversely, eye drops that contain vasoconstricting agents can render the sign more conspicuous.

Comments, questions, feedback, criticisms?

Send feedback