Connexions

Sections
You are here: Home » Content » Computational Genefinding

About: Computational Genefinding

Module by: Devika Subramanian

View content

Metadata

Name: Computational Genefinding
ID: m15083
Language: English (en)
Summary: This module is an introduction to computational genefinding. It describes the biological problem of annotating genomes into functional components. It begins with a brief description of the human genome, the central dogma of modern molecular biology, and introduces the complexities of detecting genes in eukaryotes. Ab initio methods and comparative techniques based on Hidden Markov Models are presented. GENSCAN, a classical ab initio gene finder is covered in detail. The challenges faced by comparative gene finders are described. The module ends with a discussion of how gene finders are evaluated and what the current state of the art is.
Subject: Science and Technology
Keywords: ab-initio methods, comparative methods, computational genefinding, evaluating genefinding programs, hidden markov models
Document Type: -//CNX//DTD CNXML 0.5 plus MathML//EN
License: Creative Commons Attribution License (CC-BY 2.0)
Authors: Devika Subramanian (devika@rice.edu)
Copyright Holders: Devika Subramanian (devika@rice.edu)
Maintainers: Devika Subramanian (devika@rice.edu)
Version: 1.1 (history)
Created: May 16, 2007 4:09 pm GMT-5
Revised: Sep 5, 2007 11:36 am GMT-5

Version History

Version: 1.1 Sep 5, 2007 11:36 am GMT-5 by Devika Subramanian
Changes: 
all changes verified.

How to Reuse and Attribute This Content

If you derive a copy of this content using a Connexions account and publish your version, proper attribution of the original work will be automatically done for you.

If you reuse this work elsewhere, in order to comply with the attribution requirements of the license (CC-BY 2.0), you must include

  • the authors' names: Devika Subramanian
  • the title of the work: Computational Genefinding
  • the Connexions URL where the work can be found: http://cnx.org/content/m15083/1.1/

See the citation section below for examples you can copy.

How to Cite and Attribute This Content

The following citation styles comply with the attribution requirements for the license (CC-BY 2.0) of this work:

American Chemical Society (ACS) Style Guide:

Subramanian, D. Computational Genefinding, Connexions Web site. http://cnx.org/content/m15083/1.1/, Sep 5, 2007.

American Medical Assocation (AMA) Manual of Style:

Subramanian D. Computational Genefinding [Connexions Web site]. September 5, 2007. Available at: http://cnx.org/content/m15083/1.1/.

American Psychological Assocation (APA) Publication Manual:

Subramanian, D. (2007, September 5). Computational Genefinding. Retrieved from the Connexions Web site: http://cnx.org/content/m15083/1.1/

Chicago Manual of Style (Bibliography):

Subramanian, Devika. "Computational Genefinding." Connexions. September 5, 2007. http://cnx.org/content/m15083/1.1/.

Chicago Manual of Style (Note):

Devika Subramanian, "Computational Genefinding," Connexions, September 5, 2007, http://cnx.org/content/m15083/1.1/.

Chicago Manual of Style (Reference, in Author-Date style):

Subramanian, D. 2007. Computational Genefinding. Connexions, September 5, 2007. http://cnx.org/content/m15083/1.1/.

Modern Languages Association (MLA) Style Manual:

Subramanian, Devika. Computational Genefinding. Connexions. 5 Sep. 2007 <http://cnx.org/content/m15083/1.1/>.